Spontaneous Escherichia coli cellulitis in a child with nephrotic syndrome.

Spontaneous Escherichia coli cellulitis in a child with nephrotic syndrome.

Pediatr Infect Dis J. 2007 Mar

Sleiman JN,
D'Angelo A,
Hammerschlag MR.
Department of Pediatrics, Division of Infectious Diseases, Box 49, State University of New York Downstate Medical Center, 450 Clarkson Ave., Brooklyn, NY 11203, USA. joseph.sleiman@downstate.edu

Spontaneous bacterial peritonitis is the most common infectious complication of childhood nephrotic syndrome, and Streptococcus pneumoniae is the preponderant bacterial pathogen. Spontaneous bacterial cellulitis, especially of the lower extremities, is another common infection encountered in the same patient group given that chronic edema acts as a potential culture medium. Gram-positive bacteria, including streptococci and staphylococci, are the most common causes of bacterial cellulitis. We report a case of spontaneous Escherichia coli cellulitis in a patient with steroid-dependent nephrotic syndrome.

PMID: 17484229 [PubMed - in process]

Streptococcus pneumoniae cellulitis in a diabetic patient

Streptococcus pneumoniae cellulitis in a diabetic patient
Med Mal Infect. 2007 Feb 28

Bouzat P,
Broux C,
Soriano E,
Pavese P,
Croize J,
Stahl JP,
Jacquot C.
Service de reanimation chirurgicale, departement d'anesthesie et de reanimation-I, CHU de Grenoble, BP 217 X, 38043 Grenoble cedex, France.

Pneumococcal cellulitis is an uncommon infection. Head, neck, and trunk are usually affected in patients with hematological malignancies and lupus erythematosus. Limb cellulitis is frequently observed in patients with diabetes mellitus, drug abusers, or alcoholics. Patients present with septic shock most of the time. Surgical treatment is necessary in 50% of the cases. The outcome is usually favorable. We describe the case of a 72-year-old alcoholic patient with diabetes mellitus presenting with cellulitis and septic shock.

Serotype 19 Streptococcus pneumoniae with abnormal susceptibility to penicillin (MIC: 0.75 mg/l) was isolated from cellulitis and in blood culture. The evolution was favorable after itavenous antibiotherapy combining ceftriaxone(DCI) (2 g/j), metronidazole(DCI) (1 g/j), and ciprofloxacin(DCI).

PMID: 17336015 [PubMed - as supplied by publisher]